Gymnema Extract Powder 541

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Product Origin: China
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Gymnema Extract Powder 541 Product Description
Product Name: Gymnema Extract
Mesh Analysis: Pass 80 mesh
Specification: Gymnema Acids≥25
Test Method: HPLC
Packing: 25Kg/drum
Application: dietary supplement, pharmaceutical, food and baverage, flavor and cosmetic industries.


Gymnema P.E.                                  
Latin name: Gymnema sylvestre
Chinese Pin-Yin name: Wu Xue Teng
Family: Asclepiadaceae
Genus: Gymnema
Part used: Leaves
History:
Gymnema has been used in India and South China for the treatment of diabetes for over 2,000 years. The leaves were also used for stomach ailment, constipation, water retention and liver disease.
Function:
Hypoglycemic Activity
The hypoglycemic (blood sugar-lowering) action of gymnema leaves was first documented in the late 1920s.1 This action is gradual in nature, differing from the rapid effect of many prescription hypoglycemic drugs. Gymnema leaves raise insulin levels, according to research in healthy volunteers.2 Based on animal studies, this may be due to regeneration of the cells in the pancreas that secrete insulin.3 Other animal research shows that gymnema can also improves uptake of glucose into cells and prevent adrenaline from stimulating the liver to produce glucose, thereby reducing blood sugar levels.4 It was also shown that the administration of GSE to diabetic animals not only resulted in improved glucose homeostasis, this improvement was accompanied by a regeneration of beta cells in the pancreas3.This is the only compound that has shown the ability to lessen indicators of diabetes by directly repairing/regenerating the pancreas cells responsible for producing insulin.

The leaves are also noted for lowering serum cholesterol and triglycerides.5 Some researchers have suggested gymnemic acid as one possible candidate.6 Gurmarin, another constituent of the leaves, and gymnemic acid have been shown to block the ability in humans to taste sweets.7
Dosage:
Double-blind clinical trials in India have used 400 mg per day of a water-soluble acidic extract of the gymnema leaves(standardized to 25% gymnema acids). In type 2 diabetics, ongoing use for periods as long as 18 to 24 months has proven successful.8 In type 1 (insulin-dependent) diabetes patients, a similar amount has been used successfully as an adjunct to ongoing use of insulin9 Consult closely with a physician, as insulin amounts may need to be lowered while taking gymnema extract.
Safety:
Used at the amounts suggested, gymnema is generally safe and devoid of side effects. The safety of gymnema during pregnancy and breast-feeding has not yet been determined. People with diabetes should only use gymnema extract to lower blood sugar under the clinical supervision of a healthcare professional.
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Guilin Layn Natural Ingredeints Corp.
Marshall Feng
No.22 Lijiang RD. Guilin, China
541004
86-773-5878090
86-773-5878080
www.layn.com.cn/

Gymnema Extract Powder 541

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